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Manager, PX, GWE, Manufacturing & Packaging Lead Engineer

Pfizer22h ago
United StatesOnsiteFull-timeManager Level5+ yrs exp
H-1B sponsor

ROLE SUMMARY This position provides technical leadership and engineering oversight and is fully accountable for 24x7x365 delivery of critical maintenance services within a highly environment in support of R&D manufacturing and packaging operations within a regulated pharmaceutical environment at the Groton, CT site.

The campus is comprised of 2.3M SQFT supporting an occupancy of ~2,200 colleagues and contractors and has the greatest concentration of specialty operations in the R&D network consisting of small molecule clinical manufacturing, GxP and non-regulated laboratories, vivarium, technical space (central utility plant), and office workspace facilities.

Nearly every breakthrough therapy in the R&D pipeline passes through Groton facilities and processes. This role ensures safe, compliant, and reliable operation of critical assets, while driving continuous improvement, asset lifecycle management, and engineering solutions aligned with site and enterprise objectives.

The position partners cross-functionally support manufacturing performance, regulatory compliance, and long-term reliability of production support systems. This position will manage the outcomes of work performed by supplier(s) responsible for facility maintenance and operations while providing oversight and direction for resources supporting projects from concept through turnover.

This position will have indirect budgetary responsibility for site operations and expense projects. A close working relationship with research colleagues and internal and contracted resources will facilitate the development of facility requirements, analysis of needs, recommendations, and execution of plans and options that align with overall Global Workplace Experience (GWE) objectives and goals.

This role will also ensure compliance with Pfizer internal and external regulatory requirements for GWE directed work performed on asset/systems and collaborate with key stakeholders to monitor risk, assist with operations, Business Continuity, and Crisis Management.

ROLE RESPONSIBILITIES Provide technical leadership and subject matter expertise for manufacturing and packaging equipment and systems Lead asset lifecycle management, including applicable elements of design, installation, commissioning, maintenance strategy, and obsolescence planning Partner with business line customer Manufacturing and Packaging teams to ensure equipment reliability, uptime, and performance targets Drive preventive and predictive maintenance strategies and continuous improvement initiatives Lead and support assigned elements of capital projects, including scope development, execution, and commissioning Ensure compliance with cGMP, EHS, and Pfizer Quality standards, including support for audits and inspections Lead root cause investigations and implement effective corrective and preventive actions Manage and develop a team of contractors Oversee vendor performance and service delivery, ensuring compliance with contracts and site standards Collaborate with cross-functional stakeholders, including WRDM, Business Operations, Quality, and Environmental Health & Safety (EHS) Support implementation of Lean, Six Sigma, and reliability-based methodologies Contribute to digital, automation, and smart manufacturing initiatives BASIC QUALIFICATIONS Education and Experience Bachelor’s degree in engineering (Mechanical, Chemical, Electrical, or related discipline) Minimum of 5 years’ experience demonstrated in: Pharmaceutical or regulated manufacturing/packaging environments Maintenance and engineering operations cGMP compliance Experience leading teams or providing technical leadership in a matrix organizational structure/environment Technical Skills Requirements In-depth knowledge of GxP building and facility mechanical, electrical, plumbing, and support systems and equipment Comprehensive knowledge of maintenance practices and processes Strong problem-solving and decision-making skills Understanding of Service Level Agreements (SLAs) and Key Performance Indicators (KPIs) and the ability to work with business line customers/colleagues to establish and collect meaningful metrics Proficiency in fiscal management applications and CMMS (Computerized Maintenance Management System) systems preferred Skilled proficiency with the Microsoft Office Suite including PowerPoint, Excel, and Word Soft Skills Requirements Ability to quickly adjust to a changing business climate without losing focus on near and long-term strategies Ability to exercise leadership/diplomacy in a team-oriented environment Exceptional interpersonal and negotiation skills Strong verbal and written communication skills Initiative-taking /initiative-taker with ability to multi-task and work effectively with minimal supervision Responsive customer service attitude PREFERRED QUALIFICATIONS Advanced degree (MS or MBA) Experience with: Packaging systems (e.g., filling, labeling, serialization) Automation and control systems (PLC, SCADA) Reliability engineering and asset management programs Experience leading capital projects Lean / Six Sigma certification or equivalent PHYSICAL/MENTAL REQUIREMENTS Due to the nature of work assignments, incumbents must be able to perform detailed work on multiple, concurrent tasks, with frequent interruptions and under time constraints.

On a daily basis, the position responsibilities may require the ability to stoop; to reach; to stand, to walk and sit for extended periods of time; to push and/or pull objects weighing up to 30 pounds; with reasonable accommodation; to use finger dexterity to operate a computer and other office equipment and hand strength to grasp objects; to perceive the attributes of objects by touch; to hear and verbally exchange ideas and information with colleagues and others on the phone and in the office; to see clearly from less than one foot to arm’s length with a good field of vision and to distinguish basic colors and shades of color.

On a frequent basis, essential duties of the position may require the ability to climb stairs, climb ladders, to kneel and/or crouch to retrieve items. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Day shift with occasional after hours or weekend response for onsite support associated with facility incidents or excursions or planned shutdowns for maintenance and/or capital and expense project execution Respond as required to the site in support of business continuity, emergency events, and off-shift schedules Entry and work in laboratories, vivarium, mechanical/electrical rooms, central utility plants, maintenance shops, shipping and receiving and service corridors.

While working in these areas, strict adherence to gowning procedures and personal protective equipment will be required as applicable. General safety knowledge and awareness expected in office, laboratory, and manufacturing environment Other Job Details: Last day to Apply: July 14th, 2026 Work Location Assignment: Onsite 
The annual base salary for this position ranges from $99,200.00 to $165,400.00.

In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments.

Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



 Relocation assistance may be available based on business needs and/or eligibility. 
 Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. 
 Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.

These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. 
 EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com .

This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. 
 To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers . 
Global Operations


Required skills

EngineeringGxPcGMPLeanSix SigmaAutomationControl SystemsMaintenance ManagementProject Management
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