Director of Site Management and Monitoring (DSMM)

Use Your Power for Purpose At Pfizer, our Worldwide Medical and Safety colleagues are pivotal in bridging evidence-based medical decision support with our partners and stakeholders to foster improved health and treatment outcomes. Whether you are developing the frameworks essential to validate our scientific evidence, offering unbiased and medically necessary expertise, or exploring ways to address data gaps, our mission remains clear.

We aim to empower healthcare decisions concerning the safe and appropriate use of medicines for patients. Your role will be instrumental in leading clinical trials and ensuring their progress is meticulously monitored. Your contributions will support all activities related to these trials and aid the teams of researchers conducting them.

Your leadership skills and innovative ideas will drive the growth of the Clinical Trials team at Pfizer, fostering a culture that promotes continuous improvements for the benefit of patients and healthcare. What You Will Achieve In this role, you will: Develop and lead/co-lead highly complex projects, creating mid-term plans that impact results.

Leverage relationships to meet the needs of various business units, serving as an advisor to others. Make decisions on complex problems, recommend innovative solutions, and influence management/senior staff decisions. Act independently on self-initiated projects, using knowledge from others and exercising judgment in complex decisions.

Review work for effectiveness and business impact, and evaluate the work of colleagues. Serve as a Subject Matter Expert (SME) on processes within study start-up, management, monitoring, and oversight. Partner with stakeholders to ensure understanding of study/site level signals and metrics, and gain consensus on business requirements.

Collaborate with the Business Unit Leadership Team to implement new processes and assess learning gaps and opportunities. Identify quality goals and standards, supporting a culture of high quality by improving tools for consistency and transparency.

Act as the point of accountability for monitoring and oversight quality trends, resolving escalated issues, and providing business context for required metrics/data. Here Is What You Need (Minimum Requirements) BA/BS with at least 8 years of experience or MBA/MS with at least 7 years of experience or PhD/JD with at least 5 years of experience or MD/DVM with at least 4 years of experience CRA Management experience Strong interpersonal skills and cultural awareness when collaborating across various regions and countries Attention to detail and technical expertise, such as proficiency in spreadsheets, metrics, and data flow management Excellent communication skills, both written and verbal Demonstrated ability to interpret study and site-level data, translating findings to identify potential risks Proactively identifying and mitigating risks around study execution Experience in leading and managing cross-functional teams Bonus Points If You Have (Preferred Requirements): Master’s degree (MA/MBA/MS) with over 12 years of experience or a Doctorate (PhD/PharmD/JD) with 9+ years of experience Demonstrated ability to interpret study and site-level data, translating findings to identify potential risks Proactively identifying and mitigating risks around study execution Ability to build and sustain a mentoring and buddying process for the business unit Experience in developing and implementing new processes within an organization Experience in resolving escalated process issues and questions Strong analytical skills and ability to review metrics across the organization/enterprise/portfolio for trends Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.

Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Additional Information Work Location Assignment: Remote - Field Based Last Day to Apply: July 19, 2026 
The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program.

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



This role is posted in multiple locations.

If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


 Relocation assistance may be available based on business needs and/or eligibility. 
 Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. 
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These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. 
 EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com .

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